"Wipe off": reviews, instructions for use
worries almost every teenager, but over time, the majority of the problem is eliminated by itself. In some cases, the situation requires a medical solution, because acne leaves visible scars on the skin or does not go away with transitional age. For this purpose, the drug “Sotret” was developed. The responses of those treated for it are mostly positive, and how this effect is due will be described below.
"Wipe off" reviews are recommended to be taken orally for a comprehensive solution to the problem. Patients are offered a dosage of the drug in 0.01 g or 0.02 g of the active substance in each capsule. Isotretinoin acts as an active substance. As additional components, the capsules contain:
- soybean oil;
- vegetable fat;
- beeswax and other substances.
The gelatin capsule shell consists of gelatin, edible ink, titanium dioxide, red iron oxide, paraffin, and so on.
Depending on the dosage of the main substance, the capsules, respectively, have a different number of auxiliary components.
"Erase" the instructions and reviews are positioned as an effective remedy for acne. This effect of the drug due to the ability of its component to reduce the production of sebum and facilitate its secretion. It is due to this that the inflammation around the sebaceous glands is reduced and the skin becomes more dry.Reviews of tablets "Wipe off" say that with systemic use the drug is capable of:
- effectively fight seborrhea;
- enhance skin regeneration;
- provide immunomodulatory and anti-inflammatory effects;
- show sebiostatic and keratomodulating effects.
Indications for use
"Wipe off" reviews on the application is recommended to all in the presence of severe forms of acne. You can take the tool:
The form of admission depends on the exact diagnosis made by the dermatologist. So, oral medication is taken in the presence of nodular cystic acne in the body, located throughout the body.
For perioral dermatitis, seborrhea, and pink or papulopustular acne, it should be used as an external remedy.
Rectal administration is provided for diagnoses such as rashes with seborrheic processes and recurrent acne.
The drug is sold exclusively by prescription dermatologist.
The main active ingredient of the drug is rapidly absorbed into the body through the digestive system. Taking pills with food only enhances the absorption of the drug. The highest concentration of isotretinoin in the blood is reached already in 60-240 minutes after administration. The substance is metabolized in the liver and excreted mainly in the feces (with urine in the form of metabolites). The half-life of the drug is 10-20 hours. His bioavailability is low, and the plasma protein compound is high.
Bans on use
"Erase" reviews of experts prohibit the use for the treatment of lactating women who are carrying a baby or just planning a pregnancy. Contraindications also apply to all patients undergoing antibiotic therapy from the tetracycline group or who have individual sensitivity to any component of the tablets.
In addition, it is forbidden to use the agent rectally for diseases of the rectum and orally for:
- disorders of the kidneys and liver;
- elevated plasma lipids;
- hyperavitaminosis A;
Dosage and administration
Doctors reviews about “Wipe off” are mostly positive and use the drug in their practice both for the treatment of acute forms of acne, and as maintenance therapy. The initial dose for oral administration is defined as 0.5 mg per kilogram of patient weight per day. If necessary, the dose can be increased to a maximum rate of 1 mg per 1 kg of weight, but the drug is used in such an amount only for a short time.
For maintenance therapy, it is enough to take the drug in an amount of from 0.1 mg to 1 mg. Individual dosage is prescribed only by the attending dermatologist. The daily amount of the drug can be taken once or divided into several doses, each of which should be carried out together with a meal. The duration of therapy is 16 weeks and, if necessary, may be extended, but only after a break of 1 week.
Rectal "Erase" reviews (before and after the photo can be viewed below) experts recommend using only at bedtime for 0.5-1 mg. The course of treatment lasts 8-12 weeks, and the intervals between them are 4-8 weeks.
Externally, the drug is used twice a day for 1-1.5 months.
According to reviews, "Wipe off" rarely causes negative reactions in the body, but it is worth knowing about them even before the start of the reception. Thus, the drug can cause nausea, nosebleeds, pain in muscles and joints, headaches, dry mouth, sweating, skin rashes, thinning nail plates, peeling skin on the palms or soles. Hyperostases, colitis, hepatitis, photosensitivity, depression and so on can be observed very rarely.
When using the drug rectally or externally, puffiness, redness, itching or rash may appear at the site of contact of the medication with the skin.
Reception with other medicines
With the simultaneous use of "erased" and progesterone, even in minimal doses, the effect of the first decreases markedly.
The toxic effects of the pills are enhanced while being used along with vitamin A.
In cases of parallel use of "wipe out" and antibiotics of the aminoglycoside group, the risk of intracranial hypertension increases.
In the presence of an abnormality in the kidneys or liver, the drug is used rectally and externally with extreme caution. Also in such situations one should pay attention to the presence of pancreatitis, decompensation of the heart muscle activity and any form of intoxication in the patient. Any use other than oral administration should be stopped if any side effects occur and try to resume therapy only after the recovery of the body.
Taking "Erase" orally, you should regularly monitor the amount of lipids in the blood, and if you suspect diabetes mellitus to be tested for glucose.
All recommendations for the interaction of the active substance with other medicines should be strictly considered.
Reviews of "Erase" (photo of the drug presented at the beginning of the article) from professional dermatologists indicate a possible effect of lens intolerance during therapy.Also, patients should not stay in direct sunlight for a long time and undergo UV therapy. Patients can not be during the treatment and some time after it to be blood donors for women capable of childbirth.
Caution should be exercised when treating patients with obesity, diabetes and alcoholism.
Use in children
The safety of the drug for children is not established by clinical studies. That is why the use of the drug in young patients is not practiced.
Analogs and price
The cost of capsules "Wipe off", according to reviews (photos before and after treatment are presented in the article), varies within 1000 rubles. To many, this may seem like a rather tangible amount, but the drug analogues are even more expensive. For example, Aknekutan can be found in pharmacies for as low as 1,200 rubles, and Roakkutan is even more expensive - from 1,700 rubles.
Most of the patients who have already tested the effect of the capsules on themselves were satisfied with their effectiveness. Among the shortcomings, almost everyone notes dry lips, which is a side effect, but such a slight minus does not affect the overall impression. Acne after a course of reception pass, the skin becomes not so oily, and the effect persists for a long time after the end of therapy.Among the advantages should be highlighted and the fact that the drug has a positive effect on the hair and nails. Some patients note among the advantages and cost of funds, which is significantly lower than the price of analogues.
Of course, there are also negative opinions, mainly associated with a vivid manifestation of side effects. To appreciate the therapeutic effect of the drug in such patients failed because it was necessary to cancel the reception. The negative reviews from those who tested the capsules are connected with the fact that after the treatment of acne, many have to start the treatment of the lips.Dryness does not pass even after drug withdrawal.
Also, reviews indicate that it is very difficult to find a drug in inpatient pharmacies, and it is often necessary to place orders via the Internet, which not everyone likes.